{"data":{"id":"10.6084/m9.figshare.95597","type":"dois","attributes":{"doi":"10.6084/m9.figshare.95597","prefix":"10.6084","suffix":"m9.figshare.95597","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Schweitzer, Dirk","nameType":"Personal","givenName":"Dirk","familyName":"Schweitzer","affiliation":[],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0000-0002-2406-6392","nameIdentifierScheme":"ORCID"}]}],"titles":[{"title":"Biomimetic Models of the Active Site of the Metalloenzyme Nitrile Hydratase"}],"publisher":"figshare","container":{},"publicationYear":2012,"subjects":[{"subject":"Organic Chemistry"},{"subject":"FOS: Chemical sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Chemical sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Inorganic Chemistry"}],"contributors":[],"dates":[{"date":"2012-08-31","dateType":"Created"},{"date":"2012-09-02","dateType":"Updated"},{"date":"2012","dateType":"Issued"}],"language":null,"types":{"ris":"DATA","bibtex":"misc","citeproc":"dataset","schemaOrg":"Dataset","resourceType":"Dataset","resourceTypeGeneral":"Dataset"},"relatedIdentifiers":[],"relatedItems":[],"sizes":["8238088 Bytes"],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"In the interest of a wider dissemination of the knowledge contained therein, the author's \u003cstrong\u003ePhD Thesis\u003c/strong\u003e, entitled \u003cstrong\u003e\u003cem\u003e\"Biomimetic Models of the Active Site of the Metalloenzyme Nitrile Hydratase\"\u003c/em\u003e\u003c/strong\u003e (University of Washington, Seattle, \u003cstrong\u003e2001\u003c/strong\u003e), is reproduced here. To illustrate the evolution of knowledge, the author's Precandidacy (1998) and General Exam (1999) papers and a poster (2000) are included. All of the experimental results contained within this PhD thesis have by now been reported in journal articles. However, \u003cstrong\u003e\u003cem\u003ethis thesis provided room for a much more detailed presentation of the experimental results and their discussion and analysis.\u003c/em\u003e\u003c/strong\u003e {FeNO}6 model compound [chapter 2]: \u003cem\u003eJournal of the American Chemical Society\u003c/em\u003e \u003cstrong\u003e1998\u003c/strong\u003e, \u003cem\u003e120\u003c/em\u003e, 10996-10997 http://pubs.acs.org/doi/abs/10.1021/ja981117e Oxygenated Co(III)-thiolate complexes [pages 16-17 \u0026amp; 113-116]: \u003cem\u003eJournal of the American Chemical Society\u003c/em\u003e \u003cstrong\u003e2000\u003c/strong\u003e, \u003cem\u003e122\u003c/em\u003e, 8299-8300 http://pubs.acs.org/doi/abs/10.1021/ja0017561 Improved synthesis of tetramethylammonium azide: \u003cem\u003eCroatica Chemica Acta\u003c/em\u003e \u003cstrong\u003e2001\u003c/strong\u003e, \u003cem\u003e74\u003c/em\u003e, 415-418 http://public.carnet.hr/ccacaa/CCA-PDF/cca2001/v74-n2/cca_74_2001_415-418_Schweitzer.pdf Reactivity as a function of an Et,Pr or Pr,Pr ligand backbone to model the entatic state of an enzymatic active site [chapter 3]: \u003cem\u003eInorganic Chemistry\u003c/em\u003e \u003cstrong\u003e2002\u003c/strong\u003e, \u003cem\u003e41\u003c/em\u003e, 3128-3136 http://pubs.acs.org/doi/abs/10.1021/ic0109187 Fe(III) complexes of an (Namide)2(Sthiolate)2 ligand [chapter 4]: \u003cem\u003eInorganic Chemistry\u003c/em\u003e \u003cstrong\u003e2008\u003c/strong\u003e, \u003cem\u003e47\u003c/em\u003e, 11228-11236 http://pubs.acs.org/doi/abs/10.1021/ic801704n","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"PD94bWwgdmVyc2lvbj0iMS4wIiBlbmNvZGluZz0iVVRGLTgiPz4KPHJlc291cmNlIHhtbG5zPSJodHRwOi8vZGF0YWNpdGUub3JnL3NjaGVtYS9rZXJuZWwtNCIgeG1sbnM6eHNpPSJodHRwOi8vd3d3LnczLm9yZy8yMDAxL1hNTFNjaGVtYS1pbnN0YW5jZSIgeHNpOnNjaGVtYUxvY2F0aW9uPSJodHRwOi8vZGF0YWNpdGUub3JnL3NjaGVtYS9rZXJuZWwtNCBodHRwOi8vc2NoZW1hLmRhdGFjaXRlLm9yZy9tZXRhL2tlcm5lbC00LjEvbWV0YWRhdGEueHNkIj4KICA8aWRlbnRpZmllciBpZGVudGlmaWVyVHlwZT0iRE9JIj4xMC42MDg0L005LkZJR1NIQVJFLjk1NTk3PC9pZGVudGlmaWVyPgogIDxjcmVhdG9ycz4KICAgIDxjcmVhdG9yPgogICAgICA8Y3JlYXRvck5hbWU+RGlyayBTY2h3ZWl0emVyPC9jcmVhdG9yTmFtZT4KICAgICAgPG5hbWVJZGVudGlmaWVyIG5hbWVJZGVudGlmaWVyU2NoZW1lPSJPUkNJRCIgc2NoZW1lVVJJPSJodHRwOi8vb3JjaWQub3JnIj4wMDAwLTAwMDItMjQwNi02MzkyPC9uYW1lSWRlbnRpZmllcj4KICAgIDwvY3JlYXRvcj4KICA8L2NyZWF0b3JzPgogIDx0aXRsZXM+CiAgICA8dGl0bGU+QmlvbWltZXRpYyBNb2RlbHMgb2YgdGhlIEFjdGl2ZSBTaXRlIG9mIHRoZSBNZXRhbGxvZW56eW1lIE5pdHJpbGUgSHlkcmF0YXNlPC90aXRsZT4KICA8L3RpdGxlcz4KICA8ZGVzY3JpcHRpb25zPgogICAgPGRlc2NyaXB0aW9uIGRlc2NyaXB0aW9uVHlwZT0iQWJzdHJhY3QiPiZsdDtwJmd0O0luIHRoZSBpbnRlcmVzdCBvZiBhIHdpZGVyIGRpc3NlbWluYXRpb24gb2YgdGhlIGtub3dsZWRnZSBjb250YWluZWQgdGhlcmVpbiwgdGhlIGF1dGhvcidzICZsdDtzdHJvbmcmZ3Q7UGhEIFRoZXNpcyZsdDsvc3Ryb25nJmd0OywgZW50aXRsZWQgJmx0O3N0cm9uZyZndDsmbHQ7ZW0mZ3Q7IkJpb21pbWV0aWMgTW9kZWxzIG9mIHRoZSBBY3RpdmUgU2l0ZSBvZiB0aGUgTWV0YWxsb2VuenltZSBOaXRyaWxlIEh5ZHJhdGFzZSImbHQ7L2VtJmd0OyZsdDsvc3Ryb25nJmd0OyAoVW5pdmVyc2l0eSBvZiBXYXNoaW5ndG9uLCBTZWF0dGxlLCAmbHQ7c3Ryb25nJmd0OzIwMDEmbHQ7L3N0cm9uZyZndDspLCBpcyByZXByb2R1Y2VkIGhlcmUuIFRvIGlsbHVzdHJhdGUgdGhlIGV2b2x1dGlvbiBvZiBrbm93bGVkZ2UsIHRoZSBhdXRob3IncyBQcmVjYW5kaWRhY3kgKDE5OTgpIGFuZCBHZW5lcmFsIEV4YW0gKDE5OTkpIHBhcGVycyBhbmQgYSBwb3N0ZXIgKDIwMDApIGFyZSBpbmNsdWRlZC4mbHQ7L3AmZ3Q7CiZsdDtwJmd0O0FsbCBvZiB0aGUgZXhwZXJpbWVudGFsIHJlc3VsdHMgY29udGFpbmVkIHdpdGhpbiB0aGlzIFBoRCB0aGVzaXMgaGF2ZSBieSBub3cgYmVlbiByZXBvcnRlZCBpbiBqb3VybmFsIGFydGljbGVzLiBIb3dldmVyLCAmbHQ7c3Ryb25nJmd0OyZsdDtlbSZndDt0aGlzIHRoZXNpcyBwcm92aWRlZCByb29tIGZvciBhIG11Y2ggbW9yZSBkZXRhaWxlZCBwcmVzZW50YXRpb24gb2YgdGhlIGV4cGVyaW1lbnRhbCByZXN1bHRzIGFuZCB0aGVpciBkaXNjdXNzaW9uIGFuZCBhbmFseXNpcy4mbHQ7L2VtJmd0OyZsdDsvc3Ryb25nJmd0OyZsdDsvcCZndDsKJmx0O3AmZ3Q7e0ZlTk99NiBtb2RlbCBjb21wb3VuZCBbY2hhcHRlciAyXTrCoCZsdDtlbSZndDtKb3VybmFsIG9mIHRoZSBBbWVyaWNhbiBDaGVtaWNhbCBTb2NpZXR5Jmx0Oy9lbSZndDsgJmx0O3N0cm9uZyZndDsxOTk4Jmx0Oy9zdHJvbmcmZ3Q7LCAmbHQ7ZW0mZ3Q7MTIwJmx0Oy9lbSZndDssIDEwOTk2LTEwOTk3wqAmbHQ7YSBocmVmPSJodHRwOi8vcHVicy5hY3Mub3JnL2RvaS9hYnMvMTAuMTAyMS9qYTk4MTExN2UiJmd0O2h0dHA6Ly9wdWJzLmFjcy5vcmcvZG9pL2Ficy8xMC4xMDIxL2phOTgxMTE3ZSZsdDsvYSZndDsmbHQ7L3AmZ3Q7CiZsdDtwJmd0O094eWdlbmF0ZWQgQ28oSUlJKS10aGlvbGF0ZSBjb21wbGV4ZXMgW3BhZ2VzIDE2LTE3ICZhbXA7IDExMy0xMTZdOsKgJmx0O2VtJmd0O0pvdXJuYWwgb2YgdGhlIEFtZXJpY2FuIENoZW1pY2FsIFNvY2lldHkmbHQ7L2VtJmd0O8KgJmx0O3N0cm9uZyZndDsyMDAwJmx0Oy9zdHJvbmcmZ3Q7LMKgJmx0O2VtJmd0OzEyMiZsdDsvZW0mZ3Q7LCA4Mjk5LTgzMDAgwqAmbHQ7YSBocmVmPSJodHRwOi8vcHVicy5hY3Mub3JnL2RvaS9hYnMvMTAuMTAyMS9qYTAwMTc1NjEiJmd0O2h0dHA6Ly9wdWJzLmFjcy5vcmcvZG9pL2Ficy8xMC4xMDIxL2phMDAxNzU2MSZsdDsvYSZndDsmbHQ7L3AmZ3Q7CiZsdDtwJmd0O0ltcHJvdmVkIHN5bnRoZXNpcyBvZiB0ZXRyYW1ldGh5bGFtbW9uaXVtIGF6aWRlOsKgJmx0O2VtJmd0O0Nyb2F0aWNhIENoZW1pY2EgQWN0YSZsdDsvZW0mZ3Q7wqAmbHQ7c3Ryb25nJmd0OzIwMDEmbHQ7L3N0cm9uZyZndDsswqAmbHQ7ZW0mZ3Q7NzQmbHQ7L2VtJmd0OywgNDE1LTQxOMKgJmx0O2EgaHJlZj0iaHR0cDovL3B1YmxpYy5jYXJuZXQuaHIvY2NhY2FhL0NDQS1QREYvY2NhMjAwMS92NzQtbjIvY2NhXzc0XzIwMDFfNDE1LTQxOF9TY2h3ZWl0emVyLnBkZiImZ3Q7aHR0cDovL3B1YmxpYy5jYXJuZXQuaHIvY2NhY2FhL0NDQS1QREYvY2NhMjAwMS92NzQtbjIvY2NhXzc0XzIwMDFfNDE1LTQxOF9TY2h3ZWl0emVyLnBkZiZsdDsvYSZndDsmbHQ7L3AmZ3Q7CiZsdDtwJmd0O1JlYWN0aXZpdHkgYXMgYSBmdW5jdGlvbiBvZiBhbiBFdCxQciBvciBQcixQciBsaWdhbmQgYmFja2JvbmUgdG8gbW9kZWwgdGhlIGVudGF0aWMgc3RhdGUgb2YgYW4gZW56eW1hdGljIGFjdGl2ZSBzaXRlIFtjaGFwdGVyIDNdOiAmbHQ7ZW0mZ3Q7SW5vcmdhbmljIENoZW1pc3RyeSZsdDsvZW0mZ3Q7ICZsdDtzdHJvbmcmZ3Q7MjAwMiZsdDsvc3Ryb25nJmd0OywgJmx0O2VtJmd0OzQxJmx0Oy9lbSZndDssIDMxMjgtMzEzNiAmbHQ7YSBocmVmPSJodHRwOi8vcHVicy5hY3Mub3JnL2RvaS9hYnMvMTAuMTAyMS9pYzAxMDkxODciJmd0O2h0dHA6Ly9wdWJzLmFjcy5vcmcvZG9pL2Ficy8xMC4xMDIxL2ljMDEwOTE4NyZsdDsvYSZndDsmbHQ7L3AmZ3Q7CiZsdDtwJmd0O0ZlKElJSSkgY29tcGxleGVzIG9mIGFuIChOYW1pZGUpMihTdGhpb2xhdGUpMsKgbGlnYW5kIFtjaGFwdGVyIDRdOiAmbHQ7ZW0mZ3Q7SW5vcmdhbmljIENoZW1pc3RyeSZsdDsvZW0mZ3Q7ICZsdDtzdHJvbmcmZ3Q7MjAwOCZsdDsvc3Ryb25nJmd0OywgJmx0O2VtJmd0OzQ3Jmx0Oy9lbSZndDssIDExMjI4LTExMjM2wqAmbHQ7YSBocmVmPSJodHRwOi8vcHVicy5hY3Mub3JnL2RvaS9hYnMvMTAuMTAyMS9pYzgwMTcwNG4iJmd0O2h0dHA6Ly9wdWJzLmFjcy5vcmcvZG9pL2Ficy8xMC4xMDIxL2ljODAxNzA0biZsdDsvYSZndDsmbHQ7L3AmZ3Q7CiZsdDtwJmd0O8KgJmx0Oy9wJmd0OzwvZGVzY3JpcHRpb24+CiAgPC9kZXNjcmlwdGlvbnM+CiAgPHN1YmplY3RzPgogICAgPHN1YmplY3Q+T3JnYW5pYyBDaGVtaXN0cnk8L3N1YmplY3Q+CiAgICA8c3ViamVjdD5Jbm9yZ2FuaWMgQ2hlbWlzdHJ5PC9zdWJqZWN0PgogIDwvc3ViamVjdHM+CiAgPHB1Ymxpc2hlcj5maWdzaGFyZTwvcHVibGlzaGVyPgogIDxwdWJsaWNhdGlvblllYXI+MjAxMjwvcHVibGljYXRpb25ZZWFyPgogIDxkYXRlcz4KICAgIDxkYXRlIGRhdGVUeXBlPSJDcmVhdGVkIj4yMDEyLTA4LTMxPC9kYXRlPgogICAgPGRhdGUgZGF0ZVR5cGU9IlVwZGF0ZWQiPjIwMTItMDktMDI8L2RhdGU+CiAgPC9kYXRlcz4KICA8cmVzb3VyY2VUeXBlIHJlc291cmNlVHlwZUdlbmVyYWw9IkRhdGFzZXQiPkRhdGFzZXQ8L3Jlc291cmNlVHlwZT4KICA8c2l6ZXM+CiAgICA8c2l6ZT44MjM4MDg4IEJ5dGVzPC9zaXplPgogIDwvc2l6ZXM+CiAgPHJpZ2h0c0xpc3Q+CiAgICA8cmlnaHRzIHJpZ2h0c1VSST0iaHR0cHM6Ly9jcmVhdGl2ZWNvbW1vbnMub3JnL2xpY2Vuc2VzL2J5LzQuMC8iPkNDIEJZIDQuMDwvcmlnaHRzPgogIDwvcmlnaHRzTGlzdD4KPC9yZXNvdXJjZT4=","url":"https://figshare.com/articles/dataset/Biomimetic_Models_of_the_Active_Site_of_the_Metalloenzyme_Nitrile_Hydratase/95597","contentUrl":null,"metadataVersion":3,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"mds","isActive":true,"state":"findable","reason":null,"viewCount":0,"viewsOverTime":[],"downloadCount":0,"downloadsOverTime":[],"referenceCount":0,"citationCount":0,"citationsOverTime":[],"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2012-09-02T22:25:32.000Z","registered":"2012-09-02T22:25:30.000Z","published":"2012","updated":"2020-09-05T03:27:00.000Z"},"relationships":{"client":{"data":{"id":"figshare.ars","type":"clients"}},"provider":{"data":{"id":"otjm","type":"providers"}},"media":{"data":{"id":"10.6084/m9.figshare.95597","type":"media"}},"references":{"data":[]},"citations":{"data":[]},"parts":{"data":[]},"partOf":{"data":[]},"versions":{"data":[]},"versionOf":{"data":[]}}}}