{"data":{"id":"10.6084/m9.figshare.83084.v1","type":"dois","attributes":{"doi":"10.6084/m9.figshare.83084.v1","prefix":"10.6084","suffix":"m9.figshare.83084.v1","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Hongwei Zhou","affiliation":[],"nameIdentifiers":[]},{"name":"Imrich, Amy","nameType":"Personal","givenName":"Amy","familyName":"Imrich","affiliation":[],"nameIdentifiers":[]},{"name":"Kobzik, Lester","nameType":"Personal","givenName":"Lester","familyName":"Kobzik","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"() ZK cell lines and primary AMs with MSsignificantly diminished phagocytosis of fluorescent latex beads"}],"publisher":"figshare","container":{},"publicationYear":2011,"subjects":[{"subject":"Pharmacology"},{"subject":"Immunology"},{"subject":"FOS: Clinical medicine","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Clinical medicine","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Cell Biology"}],"contributors":[],"dates":[{"date":"2011-12-31","dateType":"Created"},{"date":"2016-01-09","dateType":"Updated"},{"date":"2011","dateType":"Issued"}],"language":null,"types":{"ris":"DATA","bibtex":"misc","citeproc":"dataset","schemaOrg":"Dataset","resourceType":"Dataset","resourceTypeGeneral":"Dataset"},"relatedIdentifiers":[{"relationType":"IsPreviousVersionOf","relatedIdentifier":"10.6084/m9.figshare.83084","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":["0 Bytes"],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"Wild type primary AMs were used as control. Values shown are the means ± SD from four separate experiments. **Significant difference from WT control, \u0026lt; 0.001. () Polyinosinic acid (PolyI) had no effect but dextran sulfate (DS) increased binding by ZK1 cells. In contrast, PolyI and DS marked reduced wild-type AM binding of the latex beads. Data are expressed as the mean ± SD and compared to the control in each group (WT, MS, ZK1, respectively). *Significant difference compared with ZK1 (\u0026lt; 0.05); **Significant difference compared with WT (\u0026lt; 0.001). PolyI and DS (500 kDa), 10 μg/ml each. () The inhibition of ZK1 cells binding of the latex beads by dextran sulfate was size-dependent. Only smaller 5-8-kDa dextran sulfate was able to inhibit ZK1 cells binding of the latex beads. Data were shown as means ± SD. * \u0026lt; 0.05 versus control (n = 4). DS, 10 μg/ml.\u003cb\u003eCopyright information:\u003c/b\u003eTaken from \"Characterization of immortalized MARCO and SR-AI/II-deficient murine alveolar macrophage cell lines\"http://www.particleandfibretoxicology.com/content/5/1/7Particle and Fibre Toxicology 2008;5():7-7.Published online 2 May 2008PMCID:PMC2427050.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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","url":"https://figshare.com/articles/dataset/()_ZK_cell_lines_and_primary_AMs_with_MSsignificantly_diminished_phagocytosis_of_fluorescent_latex_beads/83084/1","contentUrl":null,"metadataVersion":4,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"mds","isActive":true,"state":"findable","reason":null,"viewCount":0,"viewsOverTime":[],"downloadCount":0,"downloadsOverTime":[],"referenceCount":0,"citationCount":0,"citationsOverTime":[],"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2016-01-09T00:26:40.000Z","registered":"2016-01-09T00:26:41.000Z","published":"2011","updated":"2020-09-05T04:33:50.000Z"},"relationships":{"client":{"data":{"id":"figshare.ars","type":"clients"}},"provider":{"data":{"id":"otjm","type":"providers"}},"media":{"data":{"id":"10.6084/m9.figshare.83084.v1","type":"media"}},"references":{"data":[]},"citations":{"data":[]},"parts":{"data":[]},"partOf":{"data":[]},"versions":{"data":[]},"versionOf":{"data":[]}}}}