{"data":{"id":"10.6084/m9.figshare.827246.v2","type":"dois","attributes":{"doi":"10.6084/m9.figshare.827246.v2","prefix":"10.6084","suffix":"m9.figshare.827246.v2","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Wallace, Chris","nameType":"Personal","givenName":"Chris","familyName":"Wallace","affiliation":[],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0000-0001-9755-1703","nameIdentifierScheme":"ORCID"}]}],"titles":[{"title":"Calculate posterior probability of association conditional on association in related disease"}],"publisher":"figshare","container":{},"publicationYear":2014,"subjects":[{"subject":"Statistics"},{"subject":"FOS: Mathematics","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Mathematics","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Genetics"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Biological sciences","subjectScheme":"Fields of Science and Technology (FOS)"}],"contributors":[],"dates":[{"date":"2014-04-04","dateType":"Created"},{"date":"2016-01-18","dateType":"Updated"},{"date":"2014","dateType":"Issued"}],"language":null,"types":{"ris":"DATA","bibtex":"misc","citeproc":"dataset","schemaOrg":"Dataset","resourceType":"Dataset","resourceTypeGeneral":"Dataset"},"relatedIdentifiers":[{"relationType":"IsIdenticalTo","relatedIdentifier":"10.6084/m9.figshare.827246","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":["14469 Bytes"],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"1 This repository contains R code used to perform numerical calculations exploring the appropriate p value thresholds for calling genetic association in one disease given genomewide significant genetic association at the same SNP in a related disease. See README.md for more details.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"PD94bWwgdmVyc2lvbj0iMS4wIiBlbmNvZGluZz0iVVRGLTgiPz4KPHJlc291cmNlIHhtbG5zPSJodHRwOi8vZGF0YWNpdGUub3JnL3NjaGVtYS9rZXJuZWwtNCIgeG1sbnM6eHNpPSJodHRwOi8vd3d3LnczLm9yZy8yMDAxL1hNTFNjaGVtYS1pbnN0YW5jZSIgeHNpOnNjaGVtYUxvY2F0aW9uPSJodHRwOi8vZGF0YWNpdGUub3JnL3NjaGVtYS9rZXJuZWwtNCBodHRwOi8vc2NoZW1hLmRhdGFjaXRlLm9yZy9tZXRhL2tlcm5lbC00LjEvbWV0YWRhdGEueHNkIj4KICA8aWRlbnRpZmllciBpZGVudGlmaWVyVHlwZT0iRE9JIj4xMC42MDg0L005LkZJR1NIQVJFLjgyNzI0Ni5WMjwvaWRlbnRpZmllcj4KICA8Y3JlYXRvcnM+CiAgICA8Y3JlYXRvcj4KICAgICAgPGNyZWF0b3JOYW1lPkNocmlzIFdhbGxhY2U8L2NyZWF0b3JOYW1lPgogICAgICA8bmFtZUlkZW50aWZpZXIgbmFtZUlkZW50aWZpZXJTY2hlbWU9Ik9SQ0lEIiBzY2hlbWVVUkk9Imh0dHA6Ly9vcmNpZC5vcmciPjAwMDAtMDAwMS05NzU1LTE3MDM8L25hbWVJZGVudGlmaWVyPgogICAgPC9jcmVhdG9yPgogIDwvY3JlYXRvcnM+CiAgPHRpdGxlcz4KICAgIDx0aXRsZT5DYWxjdWxhdGUgcG9zdGVyaW9yIHByb2JhYmlsaXR5IG9mIGFzc29jaWF0aW9uIGNvbmRpdGlvbmFsIG9uIGFzc29jaWF0aW9uIGluIHJlbGF0ZWQgZGlzZWFzZTwvdGl0bGU+CiAgPC90aXRsZXM+CiAgPGRlc2NyaXB0aW9ucz4KICAgIDxkZXNjcmlwdGlvbiBkZXNjcmlwdGlvblR5cGU9IkFic3RyYWN0Ij4mbHQ7cCZndDsxJmx0Oy9wJmd0OwombHQ7ZGl2Jmd0OwombHQ7cCZndDtUaGlzIHJlcG9zaXRvcnkgY29udGFpbnMgUiBjb2RlIHVzZWQgdG8gcGVyZm9ybSBudW1lcmljYWwgY2FsY3VsYXRpb25zIGV4cGxvcmluZyB0aGUgYXBwcm9wcmlhdGUgcCB2YWx1ZSB0aHJlc2hvbGRzIGZvciBjYWxsaW5nIGdlbmV0aWMgYXNzb2NpYXRpb24gaW4gb25lIGRpc2Vhc2UgZ2l2ZW4gZ2Vub21ld2lkZSBzaWduaWZpY2FudCBnZW5ldGljIGFzc29jaWF0aW9uIGF0IHRoZSBzYW1lIFNOUCBpbiBhIHJlbGF0ZWQgZGlzZWFzZS4mbHQ7L3AmZ3Q7CiZsdDtwJmd0O8KgJmx0Oy9wJmd0OwombHQ7cCZndDtTZWUgUkVBRE1FLm1kIGZvciBtb3JlIGRldGFpbHMuJmx0Oy9wJmd0OwombHQ7L2RpdiZndDs8L2Rlc2NyaXB0aW9uPgogIDwvZGVzY3JpcHRpb25zPgogIDxzdWJqZWN0cz4KICAgIDxzdWJqZWN0PlN0YXRpc3RpY3M8L3N1YmplY3Q+CiAgICA8c3ViamVjdD5HZW5ldGljczwvc3ViamVjdD4KICA8L3N1YmplY3RzPgogIDxwdWJsaXNoZXI+Zmlnc2hhcmU8L3B1Ymxpc2hlcj4KICA8cHVibGljYXRpb25ZZWFyPjIwMTQ8L3B1YmxpY2F0aW9uWWVhcj4KICA8ZGF0ZXM+CiAgICA8ZGF0ZSBkYXRlVHlwZT0iQ3JlYXRlZCI+MjAxNC0wNC0wNDwvZGF0ZT4KICAgIDxkYXRlIGRhdGVUeXBlPSJVcGRhdGVkIj4yMDE2LTAxLTE4PC9kYXRlPgogIDwvZGF0ZXM+CiAgPHJlc291cmNlVHlwZSByZXNvdXJjZVR5cGVHZW5lcmFsPSJEYXRhc2V0Ij5EYXRhc2V0PC9yZXNvdXJjZVR5cGU+CiAgPHNpemVzPgogICAgPHNpemU+MTQ0NjkgQnl0ZXM8L3NpemU+CiAgPC9zaXplcz4KICA8cmVsYXRlZElkZW50aWZpZXJzPgogICAgPHJlbGF0ZWRJZGVudGlmaWVyIHJlbGF0ZWRJZGVudGlmaWVyVHlwZT0iRE9JIiByZWxhdGlvblR5cGU9IklzSWRlbnRpY2FsVG8iPjEwLjYwODQvbTkuZmlnc2hhcmUuODI3MjQ2PC9yZWxhdGVkSWRlbnRpZmllcj4KICA8L3JlbGF0ZWRJZGVudGlmaWVycz4KICA8cmlnaHRzTGlzdD4KICAgIDxyaWdodHMgcmlnaHRzVVJJPSJodHRwczovL2NyZWF0aXZlY29tbW9ucy5vcmcvbGljZW5zZXMvYnkvNC4wLyI+Q0MgQlkgNC4wPC9yaWdodHM+CiAgPC9yaWdodHNMaXN0Pgo8L3Jlc291cmNlPg==","url":"https://figshare.com/articles/dataset/Calculate_posterior_probability_of_association_conditional_on_association_in_related_disease/827246/2","contentUrl":null,"metadataVersion":1,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"mds","isActive":true,"state":"findable","reason":null,"viewCount":8,"viewsOverTime":[{"yearMonth":"2025-06","total":3},{"yearMonth":"2025-10","total":1},{"yearMonth":"2025-12","total":1},{"yearMonth":"2026-01","total":2},{"yearMonth":"2026-06","total":1}],"downloadCount":1,"downloadsOverTime":[{"yearMonth":"2025-06","total":1},{"yearMonth":"2025-10","total":0},{"yearMonth":"2025-12","total":0},{"yearMonth":"2026-01","total":0},{"yearMonth":"2026-06","total":0}],"referenceCount":0,"citationCount":0,"citationsOverTime":[],"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2016-01-18T17:07:56.000Z","registered":"2016-01-18T17:07:57.000Z","published":"2014","updated":"2020-09-05T01:12:06.000Z"},"relationships":{"client":{"data":{"id":"figshare.ars","type":"clients"}},"provider":{"data":{"id":"otjm","type":"providers"}},"media":{"data":{"id":"10.6084/m9.figshare.827246.v2","type":"media"}},"references":{"data":[]},"citations":{"data":[]},"parts":{"data":[]},"partOf":{"data":[]},"versions":{"data":[]},"versionOf":{"data":[]}}}}