{"data":{"id":"10.6084/m9.figshare.750470","type":"dois","attributes":{"doi":"10.6084/m9.figshare.750470","prefix":"10.6084","suffix":"m9.figshare.750470","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Daza, Daniel Ocampo","nameType":"Personal","givenName":"Daniel Ocampo","familyName":"Daza","affiliation":[],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0000-0002-6521-8807","nameIdentifierScheme":"ORCID"}]},{"name":"Larhammar, Dan","nameType":"Personal","givenName":"Dan","familyName":"Larhammar","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"In silico searches for putative growth hormone family homologs in invertebrates"}],"publisher":"figshare","container":{},"publicationYear":2013,"subjects":[{"subject":"Molecular Biology"},{"subject":"60102 Bioinformatics","subjectScheme":"FOR"},{"subject":"FOS: Computer and information sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Computer and information sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Evolutionary Biology"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Biological sciences","subjectScheme":"Fields of Science and Technology (FOS)"}],"contributors":[],"dates":[{"date":"2013-07-23","dateType":"Created"},{"date":"2017-01-09","dateType":"Updated"},{"date":"2013","dateType":"Issued"}],"language":null,"types":{"ris":"DATA","bibtex":"misc","citeproc":"dataset","schemaOrg":"Dataset","resourceType":"Dataset","resourceTypeGeneral":"Dataset"},"relatedIdentifiers":[],"relatedItems":[],"sizes":["142139 Bytes"],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"Growth hormone, prolactin and somatolactin-family sequences were sought in diverse invertebrate genome and reference sequence databases using different available strategies. None of these search strategies could identify any putative invertebrate GH/PRL/SL homologs with the characteristic amino acid motif of the family, or indeed any significant sequence similarity. One sequence with high sequence identity to human PRL was identified from a tapeworm species; however this sequence is likely the result of horizontal gene transfer or contamination. \u003cstrong\u003eFile information:\u003c/strong\u003e \u003cstrong\u003eIn silico searches for putative growth hormone family homologs in invertebrates.pdf\u003c/strong\u003e\u003cbr\u003eDescription of methods and results, with references. \u003cstrong\u003e130723_Taenia_prl-hit_NJtree.phb\u003c/strong\u003e\u003cbr\u003eNeighbor joining tree file in Newick format including the identified tapeworm sequence. Vertebrate species names are abbreviated to the first letter of the genus followed by the first two letters of the species (Hsa = Homo sapiens et. c.). The tapeworm sequence is identified with the UniProt ID Q8T110_9CEST. \u003cstrong\u003e130723_Taenia_prl-hit_NJtree.pdf\u003c/strong\u003e\u003cbr\u003eImage of the neighbor joining tree (PDF). The tapeworm sequence is colored green. \u003cstrong\u003ePairwise_align_hPRL+Taenia_prl-hit.txt\u003c/strong\u003e\u003cbr\u003eText file with the results of the pairwise alignment between the human PRL sequence and the identified tapeworm sequence. \u003cstrong\u003eHsaPRL+Taenia_prl-hit.aln\u003c/strong\u003e\u003cbr\u003eClustal alignment file containing the human PRL sequence and the identified tapeworm sequence.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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","url":"https://figshare.com/articles/dataset/In_silico_searches_for_putative_growth_hormone_family_homologs_in_invertebrates/750470","contentUrl":null,"metadataVersion":2,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"mds","isActive":true,"state":"findable","reason":null,"viewCount":0,"viewsOverTime":[],"downloadCount":0,"downloadsOverTime":[],"referenceCount":0,"citationCount":0,"cit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