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This data was originally supplementary material for a paper in cytokine and growth factor reviews entitled \"Unchaining the beast; insights from structural and evolutionary studies on TGFβ secretion, sequestration, and activation.\" Robertson I B, Rifkin D B. (http://dx.doi.org/10.1016/j.cytogfr.2013.06.003), but for editorial reasons it was not included in the final article. For figure description please see individual figshare entries: Data file for TGFbeta superfamily tree: http://dx.doi.org/10.6084/m9.figshare.745316 CEM mutations: http://dx.doi.org/10.6084/m9.figshare.745297 GARP evolution: http://dx.doi.org/10.6084/m9.figshare.745299 Integrin activation table: http://dx.doi.org/10.6084/m9.figshare.745300 TSP1 evolution http://dx.doi.org/10.6084/m9.figshare.745314 ROS sensitivity: http://dx.doi.org/10.6084/m9.figshare.745315","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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","url":"https://figshare.com/articles/dataset/Evolution_of_TGFbeta_and_other_relevant_molecules/745298","contentUrl":null,"metadataVersion":2,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"mds","isActive":true,"state":"findable","reason":null,"viewCount":0,"viewsOverTime":[],"downloadCount":0,"downloadsOverTime":[],"referenceCount":0,"citationCount":0,"citationsOverTime":[],"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2013-07-14T21:04:55.000Z","registered":"2013-07-14T21:04:56.000Z","published":"2013","updated":"2020-09-05T01:46:42.000Z"},"relationships":{"client":{"data":{"id":"figshare.ars","type":"clients"}},"provider":{"data":{"id":"otjm","type":"providers"}},"media":{"data":{"id":"10.6084/m9.figshare.745298","type":"media"}},"references":{"data":[]},"citations":{"data":[]},"parts":{"data":[]},"partOf":{"data":[]},"versions":{"data":[]},"versionOf":{"data":[]}}}}