{"data":{"id":"10.6084/m9.figshare.628069.v1","type":"dois","attributes":{"doi":"10.6084/m9.figshare.628069.v1","prefix":"10.6084","suffix":"m9.figshare.628069.v1","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Pelsue, Stephen","nameType":"Personal","givenName":"Stephen","familyName":"Pelsue","affiliation":[],"nameIdentifiers":[]},{"name":"Hill, Beth L.","nameType":"Personal","givenName":"Beth L.","familyName":"Hill","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"STAT6 turnover"}],"publisher":"figshare","container":{},"publicationYear":2013,"subjects":[{"subject":"Molecular Biology"},{"subject":"Immunology"},{"subject":"FOS: Clinical medicine","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Clinical medicine","subjectScheme":"Fields of Science and Technology (FOS)"}],"contributors":[],"dates":[{"date":"2013-02-21","dateType":"Created"},{"date":"2016-01-11","dateType":"Updated"},{"date":"2013","dateType":"Issued"}],"language":null,"types":{"ris":"DATA","bibtex":"misc","citeproc":"dataset","schemaOrg":"Dataset","resourceType":"Dataset","resourceTypeGeneral":"Dataset"},"relatedIdentifiers":[{"relationType":"IsPreviousVersionOf","relatedIdentifier":"10.6084/m9.figshare.628069","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":["0 Bytes"],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"\u003cstrong\u003eDecay of Stat6 activation in Ttc7-fsn B cells.\u003c/strong\u003e Purified splenic B cells were stimulated with IL-4 for 30 minutes, washed 3X and allowed to rest for 15 or 30 minutes, then stained for Stat6 (red) and the nucleus (green) and imaged with confocal microscopy using a 60x objective. Co-localization of Stat6 with nucleus, denoting activation, is yellow. Ttc7fsn cells show a similar trend to WT cells at both time points, indicating they have the inherent ability to downregulate Stat6 activation when IL-4 stimulus is removed.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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","url":"https://figshare.com/articles/dataset/STAT6_turnover/628069/1","contentUrl":null,"metadataVersion":2,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"mds","isActive":true,"state":"findable","reason":null,"viewCount":0,"viewsOverTime":[],"downloadCount":0,"downloadsOverTime":[],"referenceCount":0,"citationCount":0,"citationsOverTime":[],"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2016-01-11T17:36:07.000Z","registered":"2016-01-11T17:36:08.000Z","published":"2013","updated":"2020-09-05T02:45:38.000Z"},"relationships":{"client":{"data":{"id":"figshare.ars","type":"clients"}},"provider":{"data":{"id":"otjm","type":"providers"}},"media":{"data":{"id":"10.6084/m9.figshare.628069.v1","type":"media"}},"references":{"data":[]},"citations":{"data":[]},"parts":{"data":[]},"partOf":{"data":[]},"versions":{"data":[]},"versionOf":{"data":[]}}}}