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In all, 10 clinical trials were included in a total of 1.626 patients coinfected with Hepatitis C Virus/Human Immunodeficiency Virus, mostly, carriers of genotype 1, and treated mainly for 12 or 24 weeks. Patients presented rates of approximately 91% for efficacy outcomes, while discontinuations due to adverse events were less than 3%. In this way, interferon-free therapies appear as a good option for the treatment of chronic hepatitis C in the group of patients coinfected with Human Immunodeficiency Virus.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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","url":"https://scielo.figshare.com/articles/dataset/Systematic_review_of_the_efficacy_and_safety_of_interferon-free_therapies_for_chronic_hepatitis_C_in_patients_coinfected_with_the_Human_Immunodeficiency_Virus/5885479","contentUrl":null,"metadataVersion":2,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"mds","isActive":true,"state":"findable","reason":null,"viewCount":0,"viewsOverTime":[],"downloadCount":0,"downloadsOverTime":[],"referenceCount":0,"citationCount":0,"citationsOverTime":[],"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2018-02-14T02:41:08.000Z","registered":"2018-02-14T02:41:09.000Z","published":"2018","updated":"2021-03-23T15:58:08.000Z"},"relationships":{"client":{"data":{"id":"figshare.ars","type":"clients"}},"provider":{"data":{"id":"otjm","type":"providers"}},"media":{"data":{"id":"10.6084/m9.figshare.5885479","type":"media"}},"references":{"data":[]},"citations":{"data":[]},"parts":{"data":[]},"partOf":{"data":[]},"versions":{"data":[]},"versionOf":{"data":[]}}}}