{"data":{"id":"10.6084/m9.figshare.3997179.v1","type":"dois","attributes":{"doi":"10.6084/m9.figshare.3997179.v1","prefix":"10.6084","suffix":"m9.figshare.3997179.v1","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Salahuddin, Nehal","nameType":"Personal","givenName":"Nehal","familyName":"Salahuddin","affiliation":[],"nameIdentifiers":[]},{"name":"Elbarbary, Ahmed A.","nameType":"Personal","givenName":"Ahmed A.","familyName":"Elbarbary","affiliation":[],"nameIdentifiers":[]},{"name":"Hend A. Alkabes","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"Antibacterial and Anticancer Activity of Loaded Quinazolinone Polypyrrole/Chitosan Silver Chloride Nanocomposite"}],"publisher":"Taylor \u0026 Francis","container":{},"publicationYear":2016,"subjects":[{"subject":"Biophysics"},{"subject":"Biochemistry"},{"subject":"Space Science"},{"subject":"29999 Physical Sciences not elsewhere classified","subjectScheme":"FOR"},{"subject":"FOS: Physical sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Physical sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Molecular Biology"},{"subject":"Pharmacology"},{"subject":"59999 Environmental Sciences not elsewhere classified","subjectScheme":"FOR"},{"subject":"FOS: Earth and related environmental sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Earth and related environmental sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"39999 Chemical Sciences not elsewhere classified","subjectScheme":"FOR"},{"subject":"FOS: Chemical sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Chemical sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Ecology"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Biological sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"69999 Biological Sciences not elsewhere classified","subjectScheme":"FOR"},{"subject":"Developmental Biology"},{"subject":"Inorganic Chemistry"}],"contributors":[],"dates":[{"date":"2016-10-07","dateType":"Created"},{"date":"2016-10-07","dateType":"Updated"},{"date":"2016","dateType":"Issued"}],"language":null,"types":{"ris":"DATA","bibtex":"misc","citeproc":"dataset","schemaOrg":"Dataset","resourceType":"Dataset","resourceTypeGeneral":"Dataset"},"relatedIdentifiers":[{"relationType":"IsSupplementTo","relatedIdentifier":"10.1080/00914037.2016.1201831","relatedIdentifierType":"DOI"},{"relationType":"IsPreviousVersionOf","relatedIdentifier":"10.6084/m9.figshare.3997179","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":["226937 Bytes"],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"Polypyrrole/chitosan- silver chloride core shell nanocomposite (AgCl@PPC) was prepared by \u003ci\u003ein situ\u003c/i\u003e oxidative polymerization of pyrrole (Py) using ferric chloride in the presence of chitosan (CS) and silver nitrate to develop a carrier and controlled release system for 3-amino-2-phenyl-4(3H)-quinazolinone (I). For sake of comparison, polypyrrole chitosan core shell nanoparticles (PPC) were prepared and loaded by (I). Fourier transform infrared spectroscopy, X-ray diffraction and thermal gravimetric analysis confirm that I was loaded into PPC and AgCl@PPC core shell nanocomposites respectively, through physical interaction. Results revealed that loaded AgCl@PPC and PPC exhibited excellent antibacterial and anticancer efficacy against Erlich ascites carcinoma cells.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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","url":"https://tandf.figshare.com/articles/dataset/Antibacterial_and_Anticancer_Activity_of_Loaded_Quinazolinone_Polypyrrole_Chitosan_Silver_Chloride_Nanocomposite/3997179/1","contentUrl":null,"metadataVersion":4,"schemaVersion":"http://datacite.org/schema/kernel-4",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