{"data":{"id":"10.6084/m9.figshare.1626640","type":"dois","attributes":{"doi":"10.6084/m9.figshare.1626640","prefix":"10.6084","suffix":"m9.figshare.1626640","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Satbir Mor","affiliation":[],"nameIdentifiers":[]},{"name":"Nagoria, Savita","nameType":"Personal","givenName":"Savita","familyName":"Nagoria","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"Efficient and convenient synthesis, characterization, and antimicrobial evaluation of some new tetracyclic 1,4-benzothiazines"}],"publisher":"Taylor \u0026 Francis","container":{},"publicationYear":2016,"subjects":[{"subject":"Biochemistry"},{"subject":"Space Science"},{"subject":"29999 Physical Sciences not elsewhere classified","subjectScheme":"FOR"},{"subject":"FOS: Physical sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Physical sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Medicine"},{"subject":"Microbiology"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Biological sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"39999 Chemical Sciences not elsewhere classified","subjectScheme":"FOR"},{"subject":"FOS: Chemical sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Chemical sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"69999 Biological Sciences not elsewhere classified","subjectScheme":"FOR"},{"subject":"110309 Infectious Diseases","subjectScheme":"FOR"},{"subject":"FOS: Health sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Health sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"60506 Virology","subjectScheme":"FOR"}],"contributors":[],"dates":[{"date":"2015-12-18","dateType":"Created"},{"date":"2016-02-09","dateType":"Updated"},{"date":"2016","dateType":"Issued"}],"language":null,"types":{"ris":"DATA","bibtex":"misc","citeproc":"dataset","schemaOrg":"Dataset","resourceType":"Dataset","resourceTypeGeneral":"Dataset"},"relatedIdentifiers":[{"relationType":"IsSupplementTo","relatedIdentifier":"10.1080/00397911.2015.1127383","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":["6300936 Bytes"],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"In the present study, 20 new tetracyclic 1,4-benzothiazines (\u003cb\u003e4a\u003c/b\u003e–\u003cb\u003e4 t\u003c/b\u003e) were conveniently synthesized in good yields and characterized by different spectral and physical techniques. The in vitro antimicrobial evaluation of the synthesized benzothiazine derivatives was performed by serial dilution against two Gram-positive bacteria [\u003ci\u003eBacillus subtilis\u003c/i\u003e (MTCC 441) and \u003ci\u003eStaphylococcus epidermidis\u003c/i\u003e (MTCC 6880)], two Gram-negative bacteria [\u003ci\u003eEscherichia coli\u003c/i\u003e (MTCC 1652) and \u003ci\u003ePseudomonas aeruginosa\u003c/i\u003e (MTCC 424)], and two fungal strains [\u003ci\u003eCandida albicans\u003c/i\u003e (MTCC 227) and \u003ci\u003eAspergillus niger\u003c/i\u003e (MTCC 8189)]. The derivatives \u003cb\u003e4 l\u003c/b\u003e and \u003cb\u003e4 t\u003c/b\u003e were found to be more potent than standard drug, i.e., fluconazole, against \u003ci\u003eA. niger\u003c/i\u003e and \u003ci\u003eC. albicans\u003c/i\u003e, respectively.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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","url":"https://tandf.figshare.com/articles/dataset/An_Efficient_and_Convenient_Synthesis_Characterization_and_Antimicrobial_Evaluation_of_Some_New_Tetracyclic_1_4_Benzothiazines/1626640","contentUrl":null,"metadataVersion":3,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"mds","isActive":true,"state":"findable","reason":null,"viewCount":0,"viewsOverT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