{"data":{"id":"10.6084/m9.figshare.1568813.v1","type":"dois","attributes":{"doi":"10.6084/m9.figshare.1568813.v1","prefix":"10.6084","suffix":"m9.figshare.1568813.v1","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Amutha Periyasamy","affiliation":[],"nameIdentifiers":[]},{"name":"Gopisetty, Gopal","nameType":"Personal","givenName":"Gopal","familyName":"Gopisetty","affiliation":[],"nameIdentifiers":[]},{"name":"Sridevi Veluswami","affiliation":[],"nameIdentifiers":[]},{"name":"Malliga Joyimallaya Subramanium","affiliation":[],"nameIdentifiers":[]},{"name":"Thangarajan, Rajkumar","nameType":"Personal","givenName":"Rajkumar","familyName":"Thangarajan","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"Identification of candidate biomarker mass (\u003ci\u003em\u003c/i\u003e/\u003ci\u003ez\u003c/i\u003e) ranges in serous ovarian adenocarcinoma using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry profiling"}],"publisher":"Taylor \u0026 Francis","container":{},"publicationYear":2015,"subjects":[{"subject":"Hematology"},{"subject":"Mathematics"},{"subject":"FOS: Mathematics","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Mathematics","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Biological Sciences"},{"subject":"Immunology"},{"subject":"FOS: Clinical medicine","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Clinical medicine","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Ecology"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Biological sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Chemistry"},{"subject":"Physiology"},{"subject":"Genetics"},{"subject":"Cell Biology"},{"subject":"Biochemistry"}],"contributors":[],"dates":[{"date":"2015-07-04","dateType":"Created"},{"date":"2016-01-20","dateType":"Updated"},{"date":"2015","dateType":"Issued"}],"language":null,"types":{"ris":"DATA","bibtex":"misc","citeproc":"dataset","schemaOrg":"Dataset","resourceType":"Dataset","resourceTypeGeneral":"Dataset"},"relatedIdentifiers":[{"relationType":"IsSupplementTo","relatedIdentifier":"10.3109/1354750x.2015.1068862","relatedIdentifierType":"DOI"},{"relationType":"IsPreviousVersionOf","relatedIdentifier":"10.6084/m9.figshare.1568813","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":["330343 Bytes"],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"\u003ci\u003eObjective\u003c/i\u003e: To differentiate plasma from ovarian cancer and healthy individuals using MALDI-TOF mass spectroscopy.\u003ci\u003eMaterials and methods\u003c/i\u003e: MALDI-TOF was used to generate profiles of immuno-depleted plasma samples (89 cancers and 199 healthy individuals) that were fractionated using three types of magnetic beads (HIC8, WCX and IMAC-Cu).\u003ci\u003eResults\u003c/i\u003e: Differentially expressed mass ranges showing \u0026gt;1.5–2-fold change in expression from HIC8 (30), WCX (12) and IMAC-Cu (6) fractions were identified. Cross validation and recognition capability scores for the models indicated discrimination between the classes.\u003ci\u003eConclusions\u003c/i\u003e: Spectral profiles can differentiate plasma samples of ovarian cancer patients from healthy individuals.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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","url":"https://tandf.figshare.com/articles/dataset/Identification_of_candidate_biomarker_mass_i_m_i_i_z_i_ranges_in_serous_ovarian_adenocarcinoma_using_matrix_assisted_laser_desorption_ionization_time_of_flight_mass_spectrometry_profiling/1568813/1","contentUrl":null,"metadataVersion":3,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"mds","isActive":true,"state":"findable","reason":null,"viewCount":0,"viewsOverTime":[],"downloadCount":0,"downloadsOverTime":[],"referenceCount":0,"citationCount":0,"citationsOverTime":[],"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2016-01-20T07:17:15.000Z","r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