{"data":{"id":"10.6084/m9.figshare.1495495","type":"dois","attributes":{"doi":"10.6084/m9.figshare.1495495","prefix":"10.6084","suffix":"m9.figshare.1495495","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"El-Hashash, Maher A.","nameType":"Personal","givenName":"Maher A.","familyName":"El-Hashash","affiliation":[],"nameIdentifiers":[]},{"name":"Elshahawi, Manal M.","nameType":"Personal","givenName":"Manal M.","familyName":"Elshahawi","affiliation":[],"nameIdentifiers":[]},{"name":"Ragab, Eman A.","nameType":"Personal","givenName":"Eman A.","familyName":"Ragab","affiliation":[],"nameIdentifiers":[]},{"name":"Nagdy, Sanaa","nameType":"Personal","givenName":"Sanaa","familyName":"Nagdy","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"Synthesis and Antifungal Activity of Novel Quinazolin-4(3\u003ci\u003eH\u003c/i\u003e)-one Derivatives"}],"publisher":"Taylor \u0026 Francis","container":{},"publicationYear":2015,"subjects":[{"subject":"Physiology"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Biological sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"60506 Virology","subjectScheme":"FOR"},{"subject":"Biological Sciences"},{"subject":"Immunology"},{"subject":"FOS: Clinical medicine","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Clinical medicine","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Chemistry"},{"subject":"Earth and Environmental Sciences"},{"subject":"Biotechnology"},{"subject":"Pharmacology"},{"subject":"Biochemistry"}],"contributors":[],"dates":[{"date":"2015-07-28","dateType":"Created"},{"date":"2015-12-03","dateType":"Updated"},{"date":"2015","dateType":"Issued"}],"language":null,"types":{"ris":"DATA","bibtex":"misc","citeproc":"dataset","schemaOrg":"Dataset","resourceType":"Dataset","resourceTypeGeneral":"Dataset"},"relatedIdentifiers":[{"relationType":"IsSupplementTo","relatedIdentifier":"10.1080/00397911.2015.1074697","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":["17434306 Bytes"],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"A novel group of 6-iodoquinazolin-4(\u003ci\u003e3H\u003c/i\u003e)-one derivatives was prepared starting from 6-iodo-2-ethoxy-4\u003ci\u003eH\u003c/i\u003e-3,1-benzoxazin-4-one \u003cb\u003e(3)\u003c/b\u003e via action of various nitrogen nucleophiles such as primary and secondary amines, hydrazine hydrate, and its derivatives. The 3-amino-2-hydrazinyl-6-iodoquinazolin-4(\u003ci\u003e3H\u003c/i\u003e)-one \u003cb\u003e(15)\u003c/b\u003e was used as a key starting material to prepare new heterocyclic compounds. The structures of all synthesized compounds were inferred from the infrared, mass spectral, and \u003csup\u003e1\u003c/sup\u003eH NMR spectral data as well as elemental analysis. The fungicidal activities of the target compounds were preliminarily evaluated.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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","url":"https://tandf.figshare.com/articles/dataset/Synthesis_and_Antifungal_Activity_of_Novel_Quinazolin_4_3_i_H_i_one_Derivatives/1495495","contentUrl":null,"metadataVersion":6,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"mds","isActive":true,"state":"findable","reason":null,"viewCount":0,"viewsOverTime":[],"downloadCount":0,"downloadsOverTime":[],"referenceCount":0,"citationCount":0,"citationsOverTime":[],"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2015-07-28T18:07:49.000Z","registered":"2015-07-28T18:07:50.000Z","published":"2015","updated":"2020-09-04T16:22:25.000Z"},"relationships":{"client":{"data":{"id":"figshare.ars","type":"clients"}},"provider":{"data":{"id":"otjm","type":"providers"}},"media":{"data":{"id":"10.6084/m9.figshare.1495495","type":"media"}},"references":{"data":[]},"citations":{"data":[]},"parts":{"data":[]},"partOf":{"data":[]},"versions":{"data":[]},"versionOf":{"data":[]}}}}