{"data":{"id":"10.6084/m9.figshare.1476176","type":"dois","attributes":{"doi":"10.6084/m9.figshare.1476176","prefix":"10.6084","suffix":"m9.figshare.1476176","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Rodea-Palomares, Ismael","nameType":"Personal","givenName":"Ismael","familyName":"Rodea-Palomares","affiliation":[],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0000-0002-4630-7345","nameIdentifierScheme":"ORCID"}]},{"name":"Keila Martin-Betancor","affiliation":[],"nameIdentifiers":[]},{"name":"Ritz, Christian","nameType":"Personal","givenName":"Christian","familyName":"Ritz","affiliation":[],"nameIdentifiers":[]},{"name":"Leganes, Francisco","nameType":"Personal","givenName":"Francisco","familyName":"Leganes","affiliation":[],"nameIdentifiers":[]},{"name":"Fernandez-Piñas, Francisca","nameType":"Personal","givenName":"Francisca","familyName":"Fernandez-Piñas","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"SM3_ExampleScript_Data_From_Defining an additivity framework for mixture research in inducible whole-cell biosensors"}],"publisher":"figshare","container":{},"publicationYear":2015,"subjects":[{"subject":"Statistics"},{"subject":"FOS: Mathematics","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Mathematics","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Environmental Chemistry"},{"subject":"Microbiology"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Biological sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Computer Software"},{"subject":"FOS: Computer and information sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Computer and information sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Toxicology"},{"subject":"Pharmacology"},{"subject":"Biotechnology"}],"contributors":[],"dates":[{"date":"2015-07-07","dateType":"Created"},{"date":"2015-11-26","dateType":"Updated"},{"date":"2015","dateType":"Issued"}],"language":null,"types":{"ris":"DATA","bibtex":"misc","citeproc":"dataset","schemaOrg":"Dataset","resourceType":"Dataset","resourceTypeGeneral":"Dataset"},"relatedIdentifiers":[],"relatedItems":[],"sizes":["640627 Bytes"],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"Tutorial, R-script and Dataset: Fitting non-monotonic dose-response with differential maximal effects and analysis of departures from additivity based on multivariate Loewe additivity using R. From: Defining an additivity framework for mixture research in inducible whole-cell biosensors Martin-Betancor, K1; Ritz, C2; Fernández-Piñas, F1; Leganés, F1; \u0026amp; Rodea-Palomares I1* 1 Departament of Biology, Facultad de Ciencias, Universidad Autónoma de Madrid. 28049 Madrid, Spain. 2 Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Rolighedsvej 30, DK-1958 Frederiksberg C, Denmark. *Corresponding author: Ismael Rodea-Palomares Mailing address: Departamento de Biología, Facultad de Ciencias, Universidad Autónoma de Madrid. C/ Darwin, 2. 28049, Madrid. Spain. Tel.: +34 914978180\u003cbr\u003eFax: +34 914978344 E-mail: ismael.rodea@uam.es","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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","url":"https://figshare.com/articles/dataset/SM3_ExampleScript_Data_From_Defining_an_additivity_framework_for_mixture_research_in_inducible_whole_cell_biosensors/1476176","contentUrl":null,"metadataVersion":1,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"mds","isActive":true,"state":"findable","reason":null,"viewCount":0,"viewsOverTime":[],"downloadCount":0,"downloadsOverTime":[],"referenceCount":0,"citationCount":0,"citationsOverTime":[],"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2015-11-26T09:36:14.000Z","registered":"2015-11-26T09:36:15.000Z","published":"2015","updated":"2020-09-04T16:39:59.000Z"},"relationships":{"client":{"data":{"id":"figshare.ars","type":"clients"}},"provider":{"data":{"id":"otjm","type":"providers"}},"media":{"data":{"id":"10.6084/m9.figshare.1476176","type":"media"}},"references":{"data":[]},"citations":{"data":[]},"parts":{"data":[]},"partOf":{"data":[]},"ve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