{"data":{"id":"10.6084/m9.figshare.14495559.v2","type":"dois","attributes":{"doi":"10.6084/m9.figshare.14495559.v2","prefix":"10.6084","suffix":"m9.figshare.14495559.v2","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Sinta Murlistyarini","affiliation":[],"nameIdentifiers":[]},{"name":"Lulus Putri Aninda","affiliation":[],"nameIdentifiers":[]},{"name":"Ufida Aini Afridafaz","affiliation":[],"nameIdentifiers":[]},{"name":"Widyarti, Sri","nameType":"Personal","givenName":"Sri","familyName":"Widyarti","affiliation":[],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0000-0002-9100-7544","nameIdentifierScheme":"ORCID"}]},{"name":"Endharti, Agustina Tri","nameType":"Personal","givenName":"Agustina Tri","familyName":"Endharti","affiliation":[],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0000-0002-2062-5740","nameIdentifierScheme":"ORCID"}]},{"name":"Sardjono, Teguh Wahju","nameType":"Personal","givenName":"Teguh Wahju","familyName":"Sardjono","affiliation":[],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0000-0001-6727-0361","nameIdentifierScheme":"ORCID"}]}],"titles":[{"title":"The combination of ADSCs and 10% PRP increase Rb protein expression on senescent human dermal fibroblasts .xlsx"}],"publisher":"figshare","container":{},"publicationYear":2021,"subjects":[{"subject":"110304 Dermatology","subjectScheme":"FOR"},{"subject":"FOS: Clinical medicine","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Clinical medicine","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"111702 Aged Health Care","subjectScheme":"FOR"},{"subject":"FOS: Health sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Health sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Biomarkers"},{"subject":"111601 Cell Physiology","subjectScheme":"FOR"},{"subject":"FOS: Basic medicine","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Basic medicine","subjectScheme":"Fields of Science and Technology (FOS)"}],"contributors":[],"dates":[{"date":"2021-04-27","dateType":"Created"},{"date":"2021-05-20","dateType":"Updated"},{"date":"2021","dateType":"Issued"}],"language":null,"types":{"ris":"DATA","bibtex":"misc","citeproc":"dataset","schemaOrg":"Dataset","resourceType":"Dataset","resourceTypeGeneral":"Dataset"},"relatedIdentifiers":[{"relationType":"IsPreviousVersionOf","relatedIdentifier":"10.6084/m9.figshare.14495559","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":["31052 Bytes"],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"This study was performed in vitro with a randomization sample, non-blinded pre-and post-test control group. The primary culture of senescent HDFs was transfected with a combination of ADSCs and 10% PRP. The effect on migration was observed through the scratch test, while the effect of PRP on reversal senescence was observed through Sa-β-gal analysis and the expression of protein Rb with ELISA.The data obtained were analyzed using SPSS statistical software version 25. The normality test was carried out by the Shapiro Wilk test. If the \u003ci\u003eP\u003c/i\u003e value \u0026gt; 0,05, then the normality assumption is fulfilled so that an independent t-test is carried out. However, if the normality test is not fulfilled, the Mann-Whitney test is performed.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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","url":"https://figshare.com/articles/dataset/The_combination_of_ADSCs_and_10_PRP_increase_Rb_protein_expression_on_senescent_human_dermal_fibroblasts_xlsx/14495559/2","contentUrl":null,"metadataVersion":3,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"mds","isActive":true,"state":"findable","reason":null,"viewCount":0,"viewsOverTime":[],"downloadCount":0,"downloadsOverTime":[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