{"data":{"id":"10.6084/m9.figshare.1284350.v3","type":"dois","attributes":{"doi":"10.6084/m9.figshare.1284350.v3","prefix":"10.6084","suffix":"m9.figshare.1284350.v3","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"X. Wu","affiliation":[],"nameIdentifiers":[]},{"name":"M.J. Yan","affiliation":[],"nameIdentifiers":[]},{"name":"X.P. Wan","affiliation":[],"nameIdentifiers":[]},{"name":"S.Y. Lian","affiliation":[],"nameIdentifiers":[]},{"name":"A. Li","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"Cloning and tissue expression profiling of the \u003ci\u003eGnRHR\u003c/i\u003e gene of the Muscovy duck (\u003ci\u003eCairina moschata\u003c/i\u003e): polymorphism and association with egg-laying performance"}],"publisher":"Taylor \u0026 Francis","container":{},"publicationYear":2015,"subjects":[{"subject":"110309 Infectious Diseases","subjectScheme":"FOR"},{"subject":"FOS: Health sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Health sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Developmental Biology"},{"subject":"Biological Sciences"},{"subject":"Ecology"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Biological sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Chemistry"},{"subject":"Earth and Environmental Sciences"},{"subject":"Biotechnology"},{"subject":"Physiology"},{"subject":"Molecular Biology"},{"subject":"Genetics"}],"contributors":[],"dates":[{"date":"2015-04-22","dateType":"Created"},{"date":"2016-01-19","dateType":"Updated"},{"date":"2015","dateType":"Issued"}],"language":null,"types":{"ris":"DATA","bibtex":"misc","citeproc":"dataset","schemaOrg":"Dataset","resourceType":"Dataset","resourceTypeGeneral":"Dataset"},"relatedIdentifiers":[{"relationType":"IsSupplementTo","relatedIdentifier":"10.1080/00071668.2014.997674","relatedIdentifierType":"DOI"},{"relationType":"IsIdenticalTo","relatedIdentifier":"10.6084/m9.figshare.1284350","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":["538016 Bytes"],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"1. cDNA sequence of gonadotropin-releasing-hormone receptor (\u003ci\u003eGnRHR\u003c/i\u003e) gene was cloned and an association analysis between mutations and laying performance was conducted.2. A 1680-bp cDNA sequence of Muscovy duck \u003ci\u003eGnRHR\u003c/i\u003e, which encodes 415 amino acids, was obtained and characterised. Phylogenetic analysis revealed that Muscovy duck \u003ci\u003eGnRHR\u003c/i\u003e has a close relationship with \u003ci\u003eGallus gallus GnRHR\u003c/i\u003e.3. There were significantly different expression profiles between 4 age periods in the hypothalamus, pituitary, and ovary. The expression of \u003ci\u003eGnRHR\u003c/i\u003e at the age of 36 weeks (laying period) was higher than other time points in the three tissues. \u003ci\u003eGnRHR\u003c/i\u003e was expressed in 12 different tissues. The highest expression levels were observed in hypothalamus, pituitary and gonads.4. A single nucleotide polymorphism detected in the second intron was associated with egg-laying performance. Individuals with genotype TT had better egg-laying performance from individuals with genotypes CC or TC. Therefore, \u003ci\u003eGnRHR\u003c/i\u003e could be used as a marker gene for laying performance in Muscovy duck.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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","url":"https://tandf.figshare.com/articles/datas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