{"data":{"id":"10.6084/m9.figshare.1284350.v1","type":"dois","attributes":{"doi":"10.6084/m9.figshare.1284350.v1","prefix":"10.6084","suffix":"m9.figshare.1284350.v1","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"X. Wu","affiliation":[],"nameIdentifiers":[]},{"name":"M.J. Yan","affiliation":[],"nameIdentifiers":[]},{"name":"X.P. Wan","affiliation":[],"nameIdentifiers":[]},{"name":"S.Y. Lian","affiliation":[],"nameIdentifiers":[]},{"name":"A. Li","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"Cloning and tissue expression profiling of the \u003ci\u003eGnRHR\u003c/i\u003e gene of the Muscovy duck (\u003ci\u003eCairina moschata\u003c/i\u003e): Polymorphism and association with egg-laying performance"}],"publisher":"Taylor \u0026 Francis","container":{},"publicationYear":2015,"subjects":[{"subject":"110309 Infectious Diseases","subjectScheme":"FOR"},{"subject":"FOS: Health sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Health sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Developmental Biology"},{"subject":"Biological Sciences"},{"subject":"Ecology"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Biological sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Chemistry"},{"subject":"Earth and Environmental Sciences"},{"subject":"Biotechnology"},{"subject":"Physiology"},{"subject":"Molecular Biology"},{"subject":"Genetics"}],"contributors":[],"dates":[{"date":"2015-03-04","dateType":"Created"},{"date":"2016-01-19","dateType":"Updated"},{"date":"2015","dateType":"Issued"}],"language":null,"types":{"ris":"DATA","bibtex":"misc","citeproc":"dataset","schemaOrg":"Dataset","resourceType":"Dataset","resourceTypeGeneral":"Dataset"},"relatedIdentifiers":[{"relationType":"IsSupplementTo","relatedIdentifier":"10.1080/00071668.2014.997674","relatedIdentifierType":"DOI"},{"relationType":"IsPreviousVersionOf","relatedIdentifier":"10.6084/m9.figshare.1284350","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":["538016 Bytes"],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"1. The cDNA sequence of the \u003ci\u003eGnRHR\u003c/i\u003e gene was cloned and an association analysis between mutations and laying performance was conducted.2. A 1680-bp cDNA sequence of Muscovy duck \u003ci\u003eGnRHR\u003c/i\u003e, which encodes 415 amino acids, was obtained and characterised. Phylogenetic analysis revealed that Muscovy duck \u003ci\u003eGnRHR\u003c/i\u003e has a close relationship with \u003ci\u003eGallus gallus GnRHR\u003c/i\u003e.3. There were significantly different expression profiles between 4 age periods in the hypothalamus, pituitary, and ovary. The expression of \u003ci\u003eGnRHR\u003c/i\u003e at the age of 36 weeks (laying period) was higher than other time points in the three tissues. \u003ci\u003eGnRHR\u003c/i\u003e was expressed in 12 different tissues. The highest expression levels were observed in the hypothalamus, pituitary and gonads.4. A single nucleotide polymorphism detected in the second intron was associated with egg-laying performance. Individuals with the genotype TT had better egg-laying performance from individuals with the genotypes CC or TC. Therefore, \u003ci\u003eGnRHR\u003c/i\u003e could be used as a marker gene for laying performance in the Muscovy duck.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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","url":"https://tandf.figshare.com/articles/dataset/Cloning_and_t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