{"data":{"id":"10.6084/m9.figshare.1116232","type":"dois","attributes":{"doi":"10.6084/m9.figshare.1116232","prefix":"10.6084","suffix":"m9.figshare.1116232","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"S. J. Lyu","affiliation":[],"nameIdentifiers":[]},{"name":"Y. D. Tian","affiliation":[],"nameIdentifiers":[]},{"name":"S. H. Wang","affiliation":[],"nameIdentifiers":[]},{"name":"R. L. Han","affiliation":[],"nameIdentifiers":[]},{"name":"X. X. Mei","affiliation":[],"nameIdentifiers":[]},{"name":"X. T. Kang","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"A novel 2-bp indel within Krüppel-like factor 15 gene (\u003ci\u003eKLF15\u003c/i\u003e) and its associations with chicken growth and carcass traits"}],"publisher":"Taylor \u0026 Francis","container":{},"publicationYear":2014,"subjects":[{"subject":"Developmental Biology"},{"subject":"Biological Sciences"},{"subject":"Earth and Environmental Sciences"},{"subject":"Evolutionary Biology"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Biological sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Molecular Biology"},{"subject":"Genetics"}],"contributors":[],"dates":[{"date":"2014-07-24","dateType":"Created"},{"date":"2015-12-02","dateType":"Updated"},{"date":"2014","dateType":"Issued"}],"language":null,"types":{"ris":"DATA","bibtex":"misc","citeproc":"dataset","schemaOrg":"Dataset","resourceType":"Dataset","resourceTypeGeneral":"Dataset"},"relatedIdentifiers":[{"relationType":"IsSupplementTo","relatedIdentifier":"10.1080/00071668.2014.921886","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":["527757 Bytes"],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"1. The Krüppel-like factor (KLF) family of zinc-finger transcription factors plays a critical role in cell differentiation, phenotypic modulation and physiologic function. \u003ci\u003eKLF15\u003c/i\u003e has been proposed to regulate adipogenesis and gluconeogenesis. The objective of this study was to establish the association between \u003ci\u003eKLF15\u003c/i\u003e gene polymorphism and chicken growth and carcass traits.2. An F\u003csub\u003e2\u003c/sub\u003eresource population of Gushi chickens crossed with Anka broilers was used to investigate the genetic effects of the chicken \u003ci\u003eKLF15\u003c/i\u003e gene. A 2-bp indel mutation (G13781_13782del/insAG) within intron 2 was detected, and a polymerase chain reaction–restriction fragment length polymorphism method was developed to genotype the F\u003csub\u003e2\u003c/sub\u003e individuals.3. Association analysis showed that the Single Nucleotide Polymorphisms (SNP) was significantly associated with chicken growth and carcass traits. The chickens with the insAG/insAG genotype generally had a significantly higher body weight and size than other genotypes. Gene expression for each genotype showed that birds carrying insAG/insAG had a higher expression level than the other genotypes.4. The results suggested that this polymorphic site may serve as a useful target for marker assisted selection of chicken growth and carcass traits.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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","url":"https://tandf.figshare.com/articles/dataset/A_novel_2_bp_indel_within_Kr_ppel_like_factor_15_gene_i_KLF15_i_and_its_associations_with_chicken_growth_and_carcass_traits/1116232","contentUrl":null,"metadataVersion":2,"schemaVersion":"http://datacite.org/schema/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