{"data":{"id":"10.25384/sage.c.4255823.v1","type":"dois","attributes":{"doi":"10.25384/sage.c.4255823.v1","prefix":"10.25384","suffix":"sage.c.4255823.v1","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Khowaja, Meena","nameType":"Personal","givenName":"Meena","familyName":"Khowaja","affiliation":[],"nameIdentifiers":[]},{"name":"Robins, Diana L","nameType":"Personal","givenName":"Diana L","familyName":"Robins","affiliation":[],"nameIdentifiers":[]},{"name":"Adamson, Lauren B","nameType":"Personal","givenName":"Lauren B","familyName":"Adamson","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"Utilizing two-tiered screening for early detection of autism spectrum\n          disorder"}],"publisher":"Figshare","container":{},"publicationYear":2017,"subjects":[{"subject":"170199 Psychology not elsewhere classified","subjectScheme":"FOR"},{"subject":"FOS: Psychology","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"110319 Psychiatry (incl. Psychotherapy)","subjectScheme":"FOR"},{"subject":"FOS: Clinical medicine","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"111799 Public Health and Health Services not elsewhere classified","subjectScheme":"FOR"},{"subject":"FOS: Health sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Education"},{"subject":"130312 Special Education and Disability","subjectScheme":"FOR"},{"subject":"FOS: Educational sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"}],"contributors":[],"dates":[{"date":"2018-10-05","dateType":"Created"},{"date":"2018-10-05","dateType":"Updated"},{"date":"2017","dateType":"Issued"}],"language":null,"types":{"ris":"GEN","bibtex":"misc","citeproc":"article","schemaOrg":"Collection","resourceType":"Collection","resourceTypeGeneral":"Collection"},"relatedIdentifiers":[{"relationType":"IsSupplementTo","relatedIdentifier":"10.1177/1362361317712649","relatedIdentifierType":"DOI"},{"relationType":"IsIdenticalTo","relatedIdentifier":"10.25384/sage.c.4255823","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[{"rights":"CC BY 4.0","rightsUri":"https://creativecommons.org/licenses/by/4.0"}],"descriptions":[{"description":"Despite advances in autism screening practices, challenges persist, including barriers to\n          implementing universal screening in primary care and difficulty accessing services. The\n          high false positive rate of Level 1 screening methods presents especially daunting\n          difficulties because it increases the need for comprehensive autism evaluations. This\n          study explored whether two-tiered screening—combining Level 1 (Modified Checklist for\n          Autism in Toddlers, Revised with Follow-Up) and Level 2 (Screening Tool for Autism in\n          Toddlers and Young Children) measures—improves the early detection of autism. This study\n          examined a sample of 109 toddlers who screened positive on Level 1 screening and completed\n          a Level 2 screening measure prior to a diagnostic evaluation. Results indicated that\n          two-tiered screening reduced the false positive rate using published Screening Tool for\n          Autism in Toddlers and Young Children cutoffs compared to Level 1 screening alone,\n          although at a cost to sensitivity. However, alternative Screening Tool for Autism in\n          Toddlers and Young Children scoring in the two-tiered screening improved both positive\n          predictive value and sensitivity. Exploratory analyses were conducted, including\n          comparison of autism symptoms and clinical profiles across screening subsamples.\n          Recommendations regarding clinical implications of two-tiered screening and future areas\n          of research are presented.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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