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Cancer Genetics)","subjectScheme":"FOR"},{"subject":"FOS: Basic medicine","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Basic medicine","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"60412 Quantitative Genetics (incl. Disease and Trait Mapping Genetics)","subjectScheme":"FOR"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Biological sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Genetics"}],"contributors":[],"dates":[{"date":"2018-11-07","dateType":"Created"},{"date":"2018-11-07","dateType":"Updated"},{"date":"2018","dateType":"Issued"}],"language":null,"types":{"ris":"DATA","bibtex":"misc","citeproc":"dataset","schemaOrg":"Dataset","resourceType":"Dataset","resourceTypeGeneral":"Dataset"},"relatedIdentifiers":[],"relatedItems":[],"sizes":["598687595 Bytes"],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"Chromatin interactions (using Hi-C) and functional (using eQTL) data were used to identify long-range regulatory associations involving \u0026gt;20,000 GWAS variants and their target genes (i.e. eGenes) in \u0026gt;1,350 phenotypes in the GWAS Catalog. Using convex biclustering, we segregated phenotypes based on the eGenes they share, which implies a common underlying molecular mechanism. Understanding the roles the eGenes play has potential applications in understanding multimorbidities and drug repurposing.This datasource underlie the figures generated in the study","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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","url":"https://auckland.figshare.com/articles/Visualisation_files_for_multimorbidity_analysis/7308944","contentUrl":null,"metadataVersion":3,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"mds","isActive":true,"state":"findable","reason":null,"viewCount":0,"viewsOverTime":[],"downloadCount":0,"downloadsOverTime":[],"referenceCount":0,"citationCount":0,"citationsOverTime":[],"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2018-11-07T16:23:05.000Z","registered":"2018-11-07T16:23:06.000Z","published":"2018","updated":"2020-08-28T04:08:37.000Z"},"relationships":{"client":{"data":{"id":"nzau.data","type":"clients"}},"provider":{"data":{"id":"nzau","type":"providers"}},"media":{"data":{"id":"10.17608/k6.auckland.7308944","type":"media"}},"references":{"data":[]},"citations":{"data":[]},"parts":{"data":[]},"partOf":{"data":[]},"versions":{"data":[]},"versionOf":{"data":[]}}}}